Chronic kidney disease causes hypertension through multiple interconnected pathophysiological mechanisms, creating a complex bidirectional relationship. CKD leads to hypertension primarily through sodium dysregulation with extracellular volume expansion, increased sympathetic nervous system activity, and alterations in the renin-angiotensin-aldosterone system (RAAS). According to research, these pathogenic mechanisms work together to sustain the inevitable high blood pressure state … Continue reading How Does Chronic Kidney Disease Cause Hypertension?